Cardiac Disorders : Atrioventricular block first degree ;. Eye Disorders : Eye pruritus , eye swelling, ocular hyperemia, visual disturbance;. Gastrointestinal Disorders : Abdominal pain or discomfort, diarrhea , dry mouth, lip swelling, paraesthesia oral, tongue edema , vomiting ;. Immune System Disorder s: Hypersensitivity ;. Investigations : Nonspecific changes in laboratory tests including hematology, blood chemistry, liver enzymes and urinalysis , blood pressure and electrocardiogram parameters including PR, QRS and QT intervals and ST-T segment changes.
Musculoskeletal and Connective Tissue Disorders : Myalgia ;. Nervous System Disorders : Parosmia , tremor ;. Respiratory, Thoracic and Mediastinal Disorders : Dyspnea , laryngospasm , nasal congestion , sneezing , wheezing ;.
Skin and Subcutaneous Tissue Disorders : Hyperhidrosis , pruritus , rash , swelling face, urticaria. Extravasation of MultiHance may lead to injection site reactions, characterized by local pain or burning sensation, swelling, blistering, and necrosis. There is no FDA guidance on the use of Gadobenate Dimeglumine with respect to specific gender populations.
There is no FDA guidance on the use of Gadobenate Dimeglumine with respect to specific racial populations. There is no FDA guidance on the use of Gadobenate Dimeglumine in women of reproductive potentials and males. There is no FDA guidance one the use of Gadobenate Dimeglumine in patients who are immunocompromised.
There is limited information regarding Monitoring of Gadobenate Dimeglumine in the drug label. There is limited information regarding Gadobenate Dimeglumine Pharmacology in the drug label. MultiHance injection is supplied as a sterile, nonpyrogenic, clear, colorless to slightly yellow, aqueous solution intended for intravenous use only.
Each mL of MultiHance contains mg gadobenate dimeglumine and water for injection. MultiHance contains no preservatives. Gadobenate dimeglumine is chemically designated as 4RS -[4-carboxy-5,8,tris carboxymethyl - 1-phenyloxa-5,8,triazatridecanoato 5- ] gadolinate 2- dihydrogen compound with 1-deoxy methylamino -D-glucitol with a molecular weight of The structural formula is as follows:. Renal Impairment : A single intravenous dose of 0.
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Reference article, Radiopaedia. Other drugs may interact with gadobenate dimeglumine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc.
Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
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